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Pharmacological characterization of morphine-6-sulfate and codeine-6-sulfate

✍ Scribed by Amy Zuckerman; Elizabeth Bolan; Tomas de Paulis; Dennis Schmidt; Sydney Spector; Gavril W. Pasternak


Book ID
114005190
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
111 KB
Volume
842
Category
Article
ISSN
0006-8993

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## Abstract The aim of this work was to synthesize morphine‐3‐__O__‐sulfate and morphine‐6‐__O__‐sulfate for use as reference substances, and to determine the sulfate conjugates as possible heroin and morphine metabolites in plasma and urine by a validated LC‐MS/MS method. Morphine‐6‐__O__‐sulfate