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Pharmacological activity of Elaeocarpus sphaericus

โœ Scribed by R. K. Singh; S. B. Acharya; Dr S. K. Bhattacharya

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
48 KB
Volume
14
Category
Article
ISSN
0951-418X

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โœฆ Synopsis

Elaeocarpus sphaericus fruits are used in Ayurveda for mental diseases, epilepsy, asthma, hypertension, arthritis and liver diseases. Sequential petroleum ether (PE), benzene (BE), chloroform (CE), acetone (AE) and ethanol (EE) extracts (50-200 or 200 mg/kg, ip, or 200 mg/kg, po) of dried Elaeocarpus sphaericus fruits, pretreatment time 30-45 min, showed significant antiinflammatory action against both acute and sub-acute models, analgesic, barbiturate-hypnosis potentiation and antiulcerogenic activities in rats. All the extracts, except PE and EE decreased swim stress immobility in mice indicating some degree of antidepressant activity. All the extracts protected guinea-pigs against bronchospasm induced by histamine and acetylcholine aerosols. Chemically, the extracts showed the presence of glycosides, steroids, alkaloids and flavonoids.

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## Abstract For Abstract see ChemInform Abstract in Full Text.