๐”– Bobbio Scriptorium
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Antimicrobial activity of Elaeocarpus sphaericus

โœ Scribed by R. K. Singh; Gopal Nath

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
39 KB
Volume
13
Category
Article
ISSN
0951-418X

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โœฆ Synopsis

Antibacterial activity of petroleum ether (PE), benzene (BE), chloroform (CE), acetone (AE) and ethanol (EE) extracts of dried Elaeocarpus sphaericus fruit was investigated against 28 gram-positive and gramnegative bacteria using the disc diffusion and plate dilution methods.

The AE fraction showed marked antimicrobial activity against ten organisms. BE was active against Salmonella typhimurium and Morganella morganii, and EE against Plesiomonas shigelloides, Shigella flexnerii and Sh. sonneii. The alkaloids and flavonoids present in the plant appear to be of chemotherapeutic interest.

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treated animals were as follows: histamine, 0.22 zk 0.019 and 0.0098 f 0.0012; oxotremorine, 0.16 f 0.017 and 0.0062 f 0.0004; nicotine, 1.08 f 0.15 and 0.15 f 0.038; and serotonin, 12.8 f 0.29 and 0.12 =t 0.016. The toxicity of histamine was also increased by pretreatment with dichloroisoproterenol