Basic pharmacophore of some antithrombot
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Yang Jie; Hua Weiyi
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Article
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1996
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John Wiley and Sons
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English
β 298 KB
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Platelet activation, causing formation of platelet aggregates, plays a major role in occlusive thrombus formation which may induce ischemic cardiovascular diseases. Thromboxane A2 (TXA2) is an extremely potent vasoconstricting and platelet-aggregating agent so that it is important to search for a ne