Pharmacokinetics of vinpocetine and its main metabolite apovincaminic acid before and after the chronic oral administration of vinpocetine to humans

Pharmacokinetics of vinpocetine and its

Pharmacokinetics of vinpocetine and its metabolite, apovincaminic acid, in plasma and cerebrospinal fluid after intravenous infusion

✍ Margarita Polgár; László Vereczkey; István Nyáry 📂 Article 📅 1985 🏛 Elsevier Science 🌐 English ⚖ 641 KB

The pharmacokinetics of vinpocetine (ethyl apovincaminate, Cavinton) and its metabolite, apovincaminic acid, was studied in patients with cerebrovascular disorders. Vinpocetine (1 mg/kg) was infused intravenously over 25 min. The elimination half-life of the parent drug in plasma was 4.7k2.13 h. Tot

The pharmacokinetics of tiopronin and it

The pharmacokinetics of tiopronin and its principal metabolite (2-mercaptopropionic acid) after oral administration to healthy volunteers

✍ B. Hercelin; P. Leroy; A. Nicolas; C. Gavriloff; D. Chassard; J. -J. Thébault; M 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 360 KB

Effects of oral kaempferol on the pharma

Effects of oral kaempferol on the pharmacokinetics of tamoxifen and one of its metabolites, 4-hydroxytamoxifen, after oral administration of tamoxifen to rats

✍ Yongji Piao; Sang-Chul Shin; Jun-Shik Choi 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 87 KB 👁 2 views

Effects of water deprivation on the phar

Effects of water deprivation on the pharmacokinetics of theophylline and one of its metabolites, 1,3-dimethyluric acid, after intravenous and oral administration of aminophylline to rats

✍ Hye D. Choi; Hee E. Kang; Hye J. Chung; Soo K. Bae; Karen N. Shin; Myung G. Lee 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 154 KB 👁 2 views

Effects of simvastatin on the pharmacoki

Effects of simvastatin on the pharmacokinetics of diltiazem and its main metabolite, desacetyldiltiazem, after oral and intravenous administration in rats: possible role of P-glycoprotein and CYP3A4 inhibition by simvastatin

✍ Choi, Dong Hyun (author);Choi, Jin Seok (author);Li, Cheng (author);Choi, Jun Sh 📂 Article 📅 2011 🏛 Elsevier B.V. 🌐 English ⚖ 292 KB

Effects of simvastatin on the pharmacoki

Effects of simvastatin on the pharmacokinetics of diltiazem and its main metabolite, desacetyldiltiazem, after oral and intravenous administration in rats: possible role of P-glycoprotein and CYP3A4 inhibition by simvastatin

✍ Choi, Dong Hyun (author);Choi, Jin Seok (author);Li, Cheng (author);Choi, Jun Sh 📂 Article 📅 2011 🏛 Elsevier B.V. 🌐 English ⚖ 292 KB