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Pharmacokinetics of Tramadol and Its Metabolites M1, M2, and M5 in Donkeys after Intravenous and Oral Immediate Release Single-Dose Administration

โœ Scribed by Mario Giorgi; Sara Del Carlo; Micaela Sgorbini; Giuseppe Saccomanni


Book ID
113709487
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
140 KB
Volume
29
Category
Article
ISSN
0737-0806

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Pharmacokinetics and haemodynamic effect
โœ Pollen K. F. Yeung; Joe D. Z. Feng; Susan J. Buckley ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 147 KB ๐Ÿ‘ 2 views

Deacetyl diltiazem (M 1 ) is a major metabolite of the widely used calcium antagonist diltiazem (DTZ). In order to study the pharmacokinetic and haemodynamic effects of this metabolite, M 1 was administered as a single 5 mg kg -1 dose intravenously (iv) to New Zealand white rabbits (n = 5) via a mar