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Pharmacokinetics of tissue plasminogen activator in an isolated extracorporeal circuit

✍ Scribed by Geier, Bruno; Großefeld, Marcus; Barbera, Letterio; Mumme, Achim

Book ID
122203369
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
133 KB
Volume
33
Category
Article
ISSN
1097-6809

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A recent study presented plasma concentrations of tissue-type plasminogen activator in three different animal species and at several different dose levels. A three-compartment mammillary model with capacity-limited elimination (of Michaelis -Menten form) was postulated to describe the data. In the