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Pharmacokinetics of the decarboxylase inhibitor benserazide in man; its tissue distribution in the rat

โœ Scribed by D. E. Schwartz; J. C. Jordan; W. H. Ziegler


Publisher
Springer
Year
1974
Tongue
English
Weight
702 KB
Volume
7
Category
Article
ISSN
0031-6970

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A combination of levodopa and the extracerebrally acting decarboxylase inhibitor benserazide (ratio 4:1) (Madopar), was compared with levodopa alone in a controlled double-blind clinical multicenter trial on 94 patients with Parkinson's disease. During 4 months of therapy levodopa + benserazide prov