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Pharmacokinetics and tissue distribution of astemizole in the dog

✍ Scribed by Marcel Michiels; Achiel van Peer; Robert Woestenborghs; Jozef Heykants


Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
519 KB
Volume
8
Category
Article
ISSN
0272-4391

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Comments concerning β€œpharmacokinetic cha
✍ Kenneth B. Sloan; John H. Perrin πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 149 KB

In a recent paper in this Journal, Hochhaus et al.? discussed the pharmacokinetics and distribution of the soft glucocorticoid 1 in rats and dogs. The basis for the interest in an ester of a steroidal 20-carboxylic acid as a soft drug was that the anticipated rapid metabolism of 1 to the correspondi