Oral and intravenous administration of tamoxifen base and tamoxifen citrate formulated with hydroxybutenyl-beta-cyclodextrin (HBenBCD) to Sprague-Dawley rats significantly increased the oral bioavailability of tamoxifen relative to that of parent drug (no HBenBCD). When formulated with HBenBCD, the
Pharmacokinetics of tamoxifen after intravenous and oral dosing of tamoxifen–hydroxybutenyl-β-cyclodextrin formulations
✍ Scribed by Buchanan, Charles M. (author);Buchanan, Norma L. (author);Edgar, Kevin J. (author);Little, James L. (author);Malcolm, Michael O. (author);Ruble, Karen M. (author);Wacher, Vincent J. (author);Wempe, Michael F. (author)
- Publisher
- John Wiley and Sons Inc.
- Year
- 2007
- Tongue
- English
- Weight
- 364 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0022-3549
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