𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Pharmacokinetics of tamoxifen after intravenous and oral dosing of tamoxifen–hydroxybutenyl-β-cyclodextrin formulations

✍ Scribed by Buchanan, Charles M. (author);Buchanan, Norma L. (author);Edgar, Kevin J. (author);Little, James L. (author);Malcolm, Michael O. (author);Ruble, Karen M. (author);Wacher, Vincent J. (author);Wempe, Michael F. (author)


Publisher
John Wiley and Sons Inc.
Year
2007
Tongue
English
Weight
364 KB
Volume
96
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Pharmacokinetics of tamoxifen after intr
✍ Buchanan, Charles M. (author);Buchanan, Norma L. (author);Edgar, Kevin J. (autho 📂 Article 📅 2007 🏛 John Wiley and Sons Inc. 🌐 English ⚖ 364 KB

Oral and intravenous administration of tamoxifen base and tamoxifen citrate formulated with hydroxybutenyl-beta-cyclodextrin (HBenBCD) to Sprague-Dawley rats significantly increased the oral bioavailability of tamoxifen relative to that of parent drug (no HBenBCD). When formulated with HBenBCD, the

Pharmacokinetics of itraconazole after i
✍ Charles M. Buchanan; Norma L. Buchanan; Kevin J. Edgar; Sandra Klein; James L. L 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 306 KB

The current research evaluated and compared the efficacy of hydroxybutenyl-b-cyclodextrin (HBenBCD) and hydroxypropyl-b-cyclodextrin (HPBCD) as enhancers of itraconazole solubility and oral bioavailability. At 10 wt% cyclodextrin, 17-fold and 3.8-fold increases in itraconazole aqueous solubility wer

Pharmacokinetics of deramciclane in dogs
✍ Harri Kanerva; Hannele Huuskonen; Anneli Alhonen-Raatesalmi; Timo Nevalainen; Ar 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 204 KB 👁 2 views

The pharmacokinetics of a new serotonin 5-HT 2 antagonist, deramciclane, was studied. Single oral doses of 1, 3, 6 and 10 mg kg -1 and intravenous doses of 1, 3 and 6 mg kg -1 were administered in beagle dogs. Moreover, the steady state pharmacokinetics of 1, 3 and 6 mg kg -1 doses were studied. Der

Pharmacokinetics of two lorazepam formul
✍ G. Caillé; J. Spénard; Y. Lacasse; J. Brennan 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 English ⚖ 484 KB

The pharmacokinetic profiles of a sublingual and a conventional oral lorazepam tablet formulation were established following chronic administration to twelve healthy male volunteers. Fitting a multi-dose equation based on a one-compartment model to the observed data, the average elimination half-liv