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Pharmacokinetics of subcutaneously administered etanercept in subjects with psoriasis

โœ Scribed by Ivan Nestorov; Ralph Zitnik; Todd DeVries; Arline M. Nakanishi; Andrea Wang; Christopher Banfield


Book ID
108641528
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
205 KB
Volume
62
Category
Article
ISSN
0306-5251

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Hexobarbital (HB) concentrations were determined in plasma and saliva of 8 healthy subjects, following oral administration of 500 mg HB-Na. Mean plasma half-lives were 3.2 k 0.1 h, and salivary half-lives 3.3 k 0.2 h. Mean plasma clearance was 22.9 k 2.3 1 h-'. There was a linear relationship betwee