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Pharmacokinetics of rimantadine hydrochloride in patients with chronic liver disease

✍ Scribed by Wills, Robert J; Belshe, Robert; Tomlinsin, Diana; De Grazia, Francis; Lin, Amy; Wells, Sally; Milazzo, Jack; Berry, Carol


Book ID
109844170
Publisher
Nature Publishing Group
Year
1987
Tongue
English
Weight
394 KB
Volume
42
Category
Article
ISSN
0009-9236

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Pharmacokinetics of isradipine in patien
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The pharmacokinetics of the dihydropyridine calcium antagonist isradipine has been examined in 8 healthy volunteers, 7 patients with non-cirrhotic chronic liver disease (CLD), and 8 patients with biopsy-proven cirrhosis (CIR). Isradipine was simultaneously given orally (12C 5 mg) and i.v. (13C 1 mg)