Pharmacokinetic study of chloramphenicol in patients with liver disease
β Scribed by A. P. S. Narang; D. V. Datta; N. Nath; V. S. Mathur
- Publisher
- Springer
- Year
- 1981
- Tongue
- English
- Weight
- 505 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0031-6970
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π SIMILAR VOLUMES
The pharmacokinetics of the dihydropyridine calcium antagonist isradipine has been examined in 8 healthy volunteers, 7 patients with non-cirrhotic chronic liver disease (CLD), and 8 patients with biopsy-proven cirrhosis (CIR). Isradipine was simultaneously given orally (12C 5 mg) and i.v. (13C 1 mg)
The pharmacokinetics of diacerein following a single oral dose of 50 mg was studied in 12 healthy volunteers, 10 patients with a mild liver cirrhosis (Child Pugh's grade A), and 6 patients with a more severe liver cirrhosis (Child Pugh's grade B to C). Statistical analysis using a Kruskal-Wallis tes