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Pharmacokinetics of Platinum in Cancer Patients Treated with Carboplatin in Combination with High-Dose Methotrexate

✍ Scribed by Adnan El-Yazigi; Magid Amer; Cazemiro R. Martin


Book ID
114421018
Publisher
Springer US
Year
1989
Tongue
English
Weight
745 KB
Volume
06
Category
Article
ISSN
0724-8741

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Pharmacokinetics of methotrexate and its
✍ Adnan Ei-Yazigi; Magid Amer; Iman Al-Saleh; Cazemiro Martin πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 French βš– 534 KB

The pharmacokinetics of methotrexate (MX) and 7-OH methotrexate (MXOH) was studied in 18 cancer patients treated with 6-hr intravenous (i.v.) infusion of 100 mglkg (A), 80 mglkg preceded by 20 mglkg i.v. loading dose (B), and 70 mg/kg preceded by 30 mglkg i.v. loading dose (C). Simultaneous analysis