Dose-toxicity relationship of carboplatin in combination with cyclophosphamide in ovarian cancer patients
✍ Scribed by Bente T. Sørensen; Annette Strömgren; Preben Jakobsen; Anders Jakobsen
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 492 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0344-5704
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## BACKGROUND. The authors combined cisplatin and carboplatin together with cyclophosphamide to maximize platinum dose intensity in patients with advanced epithelial ovarian cancer (AOC). ## METHODS. The authors treated 26 consecutive, newly diagnosed patients with International Federation of G
Carboplatin was given as a 30-min infusion to 11 ovarian cancer patients at doses of 170-500 mg/m 2. The ages, weights, and creatinine clearances (Clef) ranged from 44 to 75 years, from 44 to 74 kg, and from 32 to 101 ml/ min, respectively. Plasma, plasma ultrafiltrate (PU), and urine samples were o