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Pharmacokinetics of phillyrin and forsythiaside followingivadministration to Beagle dog

โœ Scribed by Yun-Xia Li; Cheng Peng; Ruo-Qi Zhang; Xue Li; Xue-Hua Jiang

Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
714 KB
Volume
34
Category
Article
ISSN
0378-7966

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CNS toxicity and CSF pharmacokinetics of
CNS toxicity and CSF pharmacokinetics of intraventricular DFMO and MGBG in beagle dogs
โœ Victor A. Levin; Deborah Byrd; Julia Campbell; Richard L. Davis; Janice K. Borci ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Springer ๐ŸŒ English โš– 539 KB

We have developed a beagle dog model to study the pharmacology and toxicology of anticancer drugs administered through the 3rd or lateral ventricles. A Foltz-type reservoir was implanted SC and connected by tube into a cerebral ventricle. Drugs were administered directly into the reservoir; CSF samp