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Pharmacokinetics of oseltamivir in breast milk and maternal plasma

โœ Scribed by Laura G. Greer; Richard D. Leff; Vanessa Laibl Rogers; Scott W. Roberts; George H. McCracken Jr; George D. Wendel Jr; Jeanne S. Sheffield

Book ID
113437781
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
240 KB
Volume
204
Category
Article
ISSN
1097-6868

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Effect of milk on the pharmacokinetics of oseltamivir in healthy volunteers
โœ Kaori Morimoto; Kozue Kishimura; Takaaki Nagami; Nao Kodama; Yoichiro Ogama; Mid ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 240 KB ๐Ÿ‘ 1 views

We previously showed that oseltamivir, a prodrug of the influenza virus neuraminidase inhibitor Ro 64-0802, is a substrate of proton-coupled oligopeptide transporter (PEPT1), and its intestinal absorption in rats is markedly inhibited by administration with milk. To investigate the importance of PEP