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Pharmacokinetics of Duloxetine in Breast Milk and Plasma of Healthy Postpartum Women

โœ Scribed by Evelyn D. Lobo, Corina Loghin, Mary Pat Knadler, Tonya Quinlan, Lu Zhang, Jill Chappell, Richard Lucas, Richard F. Bergstrom


Book ID
119926847
Publisher
Springer International Publishing AG
Year
2008
Tongue
English
Weight
119 KB
Volume
47
Category
Article
ISSN
0312-5963

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Plasma and breast-milk concentrations of dothiepin and its metabolite northiaden were measured in 20 lactating women receiving the drug for post-partum depression. Samples were collected at steady-state and both compounds quantitated by HPLC. Doses of dothiepin varied from 75 mgfday to 225 mdday. Ac