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Pharmacokinetics of oral melphalan in relation to renal function in multiple myeloma patients

✍ Scribed by Österborg, Anders; Ehrsson, Hans; Eksborg, Staffan; Wallin, Inger; Mellstedt, Håkan

Book ID
123063855
Publisher
Elsevier Science
Year
1989
Weight
454 KB
Volume
25
Category
Article
ISSN
0277-5379

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Renal function in the elimination of oral melphalan in patients with multiple myeloma
✍ C. G. Adair; J. M. Bridges; Z. R. Desai 📂 Article 📅 1986 🏛 Springer 🌐 English ⚖ 329 KB

Pharmacokinetic studies in 11 patients with multiple myeloma were undertaken on the first and last days of one course of chemotherapy. The drug was administered PO in single doses of 6-14 mg daily. Melphalan concentrations were determined by high-performance liquid chromatography. The interpatient v