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Pharmacokinetics of midazolam in the aged

✍ Scribed by M. T. Smith; V. Heazlewood; M. J. Eadie; T. O'r. Brophy; J. H. Tyrer

Publisher
Springer
Year
1984
Tongue
English
Weight
757 KB
Volume
26
Category
Article
ISSN
0031-6970

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Midazolam is a water soluble benzodiazepine, with a short elimination half-life in adults and children. An IV bolus of midazolam 0.2 mg.kg-1 was administered to 10 critically ill neonates receiving intensive care who required sedation. The plasma clearance was 6.85 ml.min-1 and the elimination half-