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Pharmacokinetics of ketoprofen enantiomers in cholecystectomy patients: influence of probenecid

✍ Scribed by R. T. Foster; F. Jamali; A. S. Russell


Book ID
104811568
Publisher
Springer
Year
1989
Tongue
English
Weight
832 KB
Volume
37
Category
Article
ISSN
0031-6970

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Pharmacokinetics of ketoprofen enantiome
✍ R. T. Foster; F. Jamali; A. S. Russell; S. R. Alballa πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 516 KB

Ketoprofen (KT), a chiral nonsteroidal anti-inflammatory drug (NSAID), is marketed and used as a racemic mixture. In healthy volunteers, negligible differences have been reported between the plasma time courses of KT enantiomers. Using a stereospecific high-performance liquid chromatographic (HPLC)