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Pharmacokinetics of isosorbide dinitrate and its mononitrate metabolites after intravenous infusion

✍ Scribed by Yves Santoni; Athanassios Iliadis; Jean -Paul Cano; Roger Luccioni; Yves Frances

Book ID
112472343
Publisher
Springer
Year
1986
Tongue
English
Weight
794 KB
Volume
14
Category
Article
ISSN
1573-8744

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Pharmacokinetics of isosorbide dinitrate
Pharmacokinetics of isosorbide dinitrate after intravenous infusion in human subjects
✍ T. Taylor; L. F. Chasseaud; E. Doyle; A. Darragh; D. A. O'Kelly; D. Fitzgerald πŸ“‚ Article πŸ“… 1980 πŸ› John Wiley and Sons 🌐 English βš– 391 KB πŸ‘ 2 views

## Abstract Plasma concentrations of isosorbide dinitrate have been measured after intravenous infusion of drug at a rate of 5Β·0 mg h^βˆ’1^ for 150 min and after single equal oral doses of 12Β·5 mg of drug in solution to two normal human subjects. During the infusion, uneven plateau concentrations wer