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Pharmacokinetics of ibuprofen in man—III: Plasma protein binding

✍ Scribed by Graham F. Lockwood; Kenneth S. Albert; Gregory J. Szpunar; John G. Wagner

Book ID
112473548
Publisher
Springer
Year
1983
Tongue
English
Weight
650 KB
Volume
11
Category
Article
ISSN
1573-8744

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Stereoselective pharmacokinetics of ibup
Stereoselective pharmacokinetics of ibuprofen in rats: effect of enantiomer-enantiomer interaction in plasma protein binding
✍ Tomoo Itoh; Jun Maruyama; Yasuyuki Tsuda; Hideo Yamada 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 212 KB 👁 2 views

Stereoselective pharmacokinetics of ibuprofen (IB) enantiomers were studied in rats. Unidirectional conversion from R-ibuprofen (R-IB) to S-ibuprofen (S-IB) was observed following intravenous administration. S-IB concentrations in plasma following racemate administration were simulated according to