Pharmacokinetics of high dose methylprednisolone and use in hematological malignancies
β Scribed by P. M. Patel; P. J. Selby; M. A. Graham; C. Viner; D. R. Newell; T. J. McElwain
- Book ID
- 118283874
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 432 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0278-0232
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A commercially available 1.0 g intravenous (i.v.) dosage formulation of methylprednisolone, as the sodium hemisuccinate salt (Solu Medrol, Upjohn) was administered both parenterally and orally (pulse steroid therapy) on separate occasions, to eight elderly (mean 65 y) patients with active rheumatoid
The absolute and relative bioavailability of two methylprednisolone formulations (capsules and suspension) was determined along with its pharmacokinetics in -four arthritic female patients, following an unconventional high-dose pulse of 1 g. Plasma concentrations of the drug were measured by a sensi