𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Comparative Pharmacokinetics of Methylprednisolone Phosphate and Hemisuccinate in High Doses

✍ Scribed by Helmut Möllmann; Peter Rohdewald; Jürgen Barth; Carsten Möllmann; Matthi Verho; Hartmut Derendorf

Book ID
114421021
Publisher
Springer US
Year
1988
Tongue
English
Weight
691 KB
Volume
05
Category
Article
ISSN
0724-8741

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Pharmacokinetics of prednisolone after h
Pharmacokinetics of prednisolone after high doses of prednisolone hemisuccinate
✍ H. Derendorf; P. Rohdewald; H. Möllmann; J. Rehder; J. Barth; D. Neveling 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 437 KB

Prednisolone in the form of its hemisuccinate was given intravenously in two different doses (1200 mg and 75 mg). Plasma levels of the ester and prednisolone were measured and pharmacokinetic parameters were calculated. The results indicate a dose-dependency in the pharmacokinetics of both hemisucci

Pharmacokinetics and dose linearity test
Pharmacokinetics and dose linearity testing of methylprednisolone phosphate
✍ Helmut Möllmann; Peter Rohdewald; Jürgen Barth; Matthi Verho; Dr Hartmut Derendo 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 505 KB

The pharmacokinetics of methylprednisolone and methylprednisolone phosphate were investigated after intravenous administration of methylprednisolone phosphate to six healthy subjects at seven different doses between 16 and 1000 mg. Plasma, urine, and saliva were analyzed for methylprednisolone and m

High dose oral methylprednisolone in pat
High dose oral methylprednisolone in patients with rheumatoid arthritis: pharmacokinetics and clinical response
✍ P. J. Hayball; D. G. Cosh; M. J. Ahern; D. W. Schultz; P. J. Roberts-Thomson 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 436 KB

A commercially available 1.0 g intravenous (i.v.) dosage formulation of methylprednisolone, as the sodium hemisuccinate salt (Solu Medrol, Upjohn) was administered both parenterally and orally (pulse steroid therapy) on separate occasions, to eight elderly (mean 65 y) patients with active rheumatoid

Systemic bioavailability and pharmacokin
Systemic bioavailability and pharmacokinetics of methylprednisolone in patients with rheumatoid arthritis following ‘high-dose’ pulse administration
✍ P. K. Narang; R. Wilder; D. C. Chatterji; R. L. Yeager; J. F. Gallelli 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 English ⚖ 781 KB

The absolute and relative bioavailability of two methylprednisolone formulations (capsules and suspension) was determined along with its pharmacokinetics in -four arthritic female patients, following an unconventional high-dose pulse of 1 g. Plasma concentrations of the drug were measured by a sensi