𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Pharmacokinetics of HEPP, a new anticonvulsant, in healthy subjects and rabbits after multiple doses

✍ Scribed by Dinora F. González-Esquivel; Rodolfo Pérez M; Helgi Jung Cook

Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
87 KB
Volume
25
Category
Article
ISSN
0142-2782

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Single dose pharmacokinetics of HEPP, a
Single dose pharmacokinetics of HEPP, a new anticonvulsant in normal healthy volunteers
✍ Dinora F. González-Esquivel; Francisco Rubio-Donnadieu; Guillermo Carvajal S.; H 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 128 KB 👁 2 views

The pharmacokinetics and the dose proportionality of a new anticonvulsant compound, HEPP (D,L-3-hydroxy-3-ethyl-3-phenylpropionamide) was studied in healthy male volunteers as part of the pharmacological evaluation for new drugs. Study was performed administering doses of 250, 375, 500 and 625 mg of

Pharmacokinetics of fluvoxamine maleate
Pharmacokinetics of fluvoxamine maleate after increasing single oral doses in healthy subjects
✍ M. H. De Vries; J. Van Harten; P. Van Bemmel; M. Raghoebar 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 286 KB 👁 2 views

The pharmacokinetics of fluvoxamine after single oral administration of 25, 50, and 100mg fluvoxamine maleate was studied in a three-way cross-over study in 12 healthy male subjects. Fluvoxamine was administered orally in a solution. For doseproportionality, AUC, and C,-dose relationships were evalu

Pharmacokinetics of the novel anticonvul
Pharmacokinetics of the novel anticonvulsant hepp after single intravenous administration of three different doses in dogs
✍ Lisbeth E. Gómez M.; Pedro A. Lehmann F. 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 385 KB 👁 2 views

HEPP (D, L-3-hydroxy-3-ethyl-3-phenylpropanamide) is a novel compound with a wide spectrum of anticonvulsant activity and relatively low toxicity. The aim of this investigation was to study the pharmacokinetics of HEPP in mongrel dogs and to assess its linearity after intravenous administration of 8

Comparative pharmacokinetics of midazola
Comparative pharmacokinetics of midazolam and loprazolam in healthy subjects after oral administration
✍ R. Jochemsen; P. A. Van Rijn; T. G. M. Hazelzet; C. J. Van Boxtel; D. D. Breimer 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 397 KB 👁 1 views

The pharmacokinetics of oral midazolam (Dormicum@, 15 mg) and loprazolam (Dormonoct@, 1 mg) were studied in eight healthy young volunteers in a cross-over design. Plasma concentrations of midazolam were measured with a gas chromatographic method and loprazolam concentrations were determined by a rad

Excretion of digoxin and its metabolites
Excretion of digoxin and its metabolites in urine after a single oral dose in healthy subjects
✍ J. O. Magnusson; B. Bergdahl; C. Bogentoft; U. E. Jonsson; L. Tekenbergs 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 English ⚖ 379 KB 👁 2 views

## Abstract The 3‐day urinary excretion of digoxin, its conjugated and unconjugated hydrolytic metabolites and dihydrodigoxin, was studied in 8 healthy men after oral administration of tritiated digoxin. Analysis was performed by high pressure liquid chromatography (HPLC). The total radioactivity c