Objective: Dexamethasone is frequently used in premature neonates with bronchopulmonary dysplasia, however little is known about its disposition in this population. Methods: We evaluated the pharmacokinetics of dexamethasone in 9 premature neonates with a mean gestational age of 27.3 weeks and a pos
Pharmacokinetics of furosemide in neonates
β Scribed by P. Vert; M. Broquaire; M. Legagneur; P. L. Morselli
- Publisher
- Springer
- Year
- 1982
- Tongue
- English
- Weight
- 660 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0031-6970
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## Abstract The pharmacokinetics of furosemide were investigated in the rat at doses of 10 and 40mg kg^β1^ corresponding to doses of 80 and 320 mg given to humans based on body surface area. A threeβcompartment open model with renal excretion taking place from the shallow peripheral compartment gav