Pharmacokinetics of doxorubicin in sarcoma patients
โ Scribed by J. Robert; N. B. Bui; P. Vrignaud
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 391 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0031-6970
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The pharmacokinetics of doxorubicin (DOX), iodo-doxorubicin (I-DOX) and their metabolites in plasma has been examined in five patients each receiving 50 mg/m2 of both anthracyclines as a bolus injection. Terminal half-life, mean residence time (MRT), peak plasma concentration Cmax, and area under th
Two treatment regimens for metastatic soft-tissue sarcomas were compared in a randomized trial in the cooperative group setting. Histopathologic diagnosis was affirmed by pathology reference panel review in 72% of the 347 patients. In 21% of patients, the reference panel affirmed the diagnosis of so