Pharmacokinetics of carboplatin administered with lobradimil to pediatric patients with brain tumors
β Scribed by Katherine Warren; Anne Gervais; Alberta Aikin; Merrill Egorin; Frank M. Balis
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 248 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0344-5704
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## BACKGROUND. Carboplatinβbased regimens have demonstrated activity in pediatric patients with lowβgrade glioma (LGG). However, carboplatin hypersensitivity reaction (Cb HSR) represents a common and limiting factor for the continuation of therapy. ## METHODS. The objectives of this
## Abstract ## BACKGROUND Fotemustine is a nitrosourea with theoretic and preclinical advantages over the original analogs, carmustine and lomustine, in the treatment of brain tumors. This is the first pediatric Phase I study of fotemustine. ## METHODS Patients younger than 21 with recurrent/res