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Phase I trial of lobradimil (RMP-7) and carboplatin in children with brain tumors

✍ Scribed by Katherine E. Warren; Mahendra C. Patel; Alberta A. Aikin; Brigitte Widemann; Madeleine Libucha; Peter C. Adamson; Rachel Neuwirth; David Benziger; Timothy O'Toole; Kathleen Ford; Nicholas Patronas; Roger J. Packer; Frank M. Balis

Publisher
Springer
Year
2001
Tongue
English
Weight
132 KB
Volume
48
Category
Article
ISSN
0344-5704

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A Phase I study of concurrent RMP-7 and
A Phase I study of concurrent RMP-7 and carboplatin with radiation therapy for children with newly diagnosed brainstem gliomas
✍ Roger J. Packer; Mark Krailo; Minesh Mehta; Katherine Warren; Jeffrey Allen; Reg πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 105 KB

## Abstract ## BACKGROUND Ninety percent of children with diffuse, intrinsic brainstem tumors will die within 18 months of diagnosis. Radiotherapy is of transient benefit to these children, and a potential way to improve its efficacy is to add radiosensitizers. Carboplatin is antineoplastic and ra