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Pharmacokinetics of a new calcium channel blocker, isradipine, in patients with chronic liver disease

✍ Scribed by Qayyum, Tahir; McArdle, Peter; Hilmy, Mustafa; Going, James; Underwood, Mark; McMillan, Donald; Edwards, Joanne

Book ID
121894084
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
78 KB
Volume
5
Category
Article
ISSN
0168-8278

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Pharmacokinetics of isradipine in patien
Pharmacokinetics of isradipine in patients with chronic liver disease
✍ J. Cotting; J. Reichen; K. Kutz; R. Laplanche; E. NΓΌesch πŸ“‚ Article πŸ“… 1990 πŸ› Springer 🌐 English βš– 523 KB

The pharmacokinetics of the dihydropyridine calcium antagonist isradipine has been examined in 8 healthy volunteers, 7 patients with non-cirrhotic chronic liver disease (CLD), and 8 patients with biopsy-proven cirrhosis (CIR). Isradipine was simultaneously given orally (12C 5 mg) and i.v. (13C 1 mg)