𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Pharmacokinetics of 4′-O-tetrahydropyranyladriamycin given on a weekly schedule in patients with advanced breast cancer

✍ Scribed by Robert M. Mader; Harald Zilg; Otto Schlappack; Günther G. Steger; Martina Baur; Bertold Greifenberg; Uwe Heberle; Christian Dittrich


Publisher
Springer
Year
1995
Tongue
English
Weight
652 KB
Volume
37
Category
Article
ISSN
0344-5704

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Pharmacokinetic, biochemical and clinica
✍ Mark Clemons; Malcolm Ranson; Jennifer M. Margison; Hassan El Teraifi; Audrey Gr 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 107 KB

## Abstract We assessed whether split dosing with the methylating agent DTIC is an effective strategy for inactivating the DNA repair protein __O__6‐alkylguanine DNA‐ATase in order to decrease tumour resistance to BCNU. ATase levels in PBMCs were used as a surrogate for tumour ATase depletion to de