Pharmacokinetics and tolerance of intravenous and intramuscular recombinant alpha2 interferon in patients with malignancies
β Scribed by I. Shah; J. Band; M. Samson; J. Young; R. Robinson; B. Bailey; A. Martin Lerner; A. S. Prasad
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 467 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0361-8609
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The circulating levels of a 90-kilodalton (K) tumor-associated antigen were measured in the blood of 43 patients with gynecologic and breast malignancies who underwent a short course of recombinant alpha-2b-interferon (rIFN a-zb) (3 million U/m2/d intramuscularly [IM] for 3 days). Of the 43 patients
## Abstract Several side effects of interferonβΞ±β2b (IFNβΞ±) therapy have been described. Pulmonary side effects have seldom been reported. The four patients we describe all developed respiratory disorders while being treated with IFNβΞ± for hematological malignancies. We point out the similarities a