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Pharmacokinetics and Tolerability of the Orally Active Selective Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor ZD1839 in Healthy Volunteers

โœ Scribed by Ms Helen Swaisland, Alison Laight, Lesley Stafford, Helen Jones, Charles Morris, Aaron Dane, Roger Yates


Book ID
119926344
Publisher
Springer International Publishing AG
Year
2001
Tongue
English
Weight
202 KB
Volume
40
Category
Article
ISSN
0312-5963

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โœ Ichiro Naruse; Tohru Ohmori; Yoko Ao; Hisao Fukumoto; Toshio Kuroki; Masatomo Mo ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 216 KB ๐Ÿ‘ 1 views

## Abstract Selective tyrosine kinase inhibitors are regarded as promising antitumor agents for cancer treatment. Iressaยฎ (ZD1839) is an orally active, selective EGFRโ€TKI (epidermal growth factor receptorโ€tyrosine kinase inhibitor) that blocks signal transduction pathways implicated in cancer cell