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Pharmacokinetics and pharmacologic effects after single and chronic doses of isosorbide dinitrate

✍ Scribed by Ho-Leung Fung; Edward F. McNiff; Donald Ruggirello; Andrew Darke; John O. Parker; Udho Thadani


Book ID
115668662
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
150 KB
Volume
45
Category
Article
ISSN
0002-9149

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Pharmacokinetics of isosorbide dinitrate
✍ T. Taylor; L. F. Chasseaud; E. Doyle; A. Darragh; D. A. O'Kelly; D. Fitzgerald πŸ“‚ Article πŸ“… 1980 πŸ› John Wiley and Sons 🌐 English βš– 391 KB πŸ‘ 2 views

## Abstract Plasma concentrations of isosorbide dinitrate have been measured after intravenous infusion of drug at a rate of 5Β·0 mg h^βˆ’1^ for 150 min and after single equal oral doses of 12Β·5 mg of drug in solution to two normal human subjects. During the infusion, uneven plateau concentrations wer