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Pharmacokinetics and pharmacodynamics of ()-sotalol in healthy male volunteers

โœ Scribed by MASAHIKO KIMURA; KAZUO UMEMURA; YASUHIKO IKEDA; KAZUHIRO KOSUGE; ATSUHIRO MIZUNO; HIROSHI NAKANOMYO; KYOICHI OHASHI &; MITSUYOSHI NAKASHIMA


Book ID
108639944
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
530 KB
Volume
42
Category
Article
ISSN
0306-5251

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The pharmacokinetics of d-sotalol and d,
โœ J. M. Poirier; P. Jaillon; B. Lecocq; V. Lecocq; A. Ferry; G. Cheymol ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Springer ๐ŸŒ English โš– 376 KB

The pharmacokinetics of d-sotalol has been studied in six healthy volunteers given single doses of 0.25, 0.50, 1, 2 mg.kg-1 i.v. and one 100 mg oral dose in comparison with the kinetics of 1 mg.kg-1 i.v. of dl-sotalol. There was no significant difference in the disposition of the d-enantiomer and th