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Pharmacokinetics and Pharmacodynamics of AR9281, an Inhibitor of Soluble Epoxide Hydrolase, in Single- and Multiple-Dose Studies in Healthy Human Subjects

โœ Scribed by Chen, Dawn; Whitcomb, Randall; MacIntyre, Euan; Tran, Vinh; Do, Zung N.; Sabry, James; Patel, Dinesh V.; Anandan, Sampath K.; Gless, Richard; Webb, Heather K.


Book ID
126265141
Publisher
Sage Publications
Year
2012
Tongue
English
Weight
537 KB
Volume
52
Category
Article
ISSN
0091-2700

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Single and multiple dose pharmacokinetic
โœ C. Fracasso; S. Confalonieri; S. Garattini; S. Caccia ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer ๐ŸŒ English โš– 498 KB

The pharmacokinetics of etizolam, a new thienodiazepine derivative, has been examined after single and multiple (0.5 mg tablet) (0.5 mg b.d for 1 week) oral therapeutic doses in healthy volunteers. The single-dose kinetic profile of etizolam suggested that absorption after oral dosage was reasonably