Pharmacokinetics and metabolism of bisoprolol enantiomers in humans
โ Scribed by Yuji Horikiri; Takehiko Suzuki; Masakazu Mizobe
- Book ID
- 109388936
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 70 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0022-3549
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๐ SIMILAR VOLUMES
The chiral beta-blocker acebutolol (AC) is marketed as a racemic mixture. Both AC and its major metabolite, diacetotol (DC), are chiral, the S-enantiomer possessing beta-blocking activity. The pharmacokinetics of AC and DC enantiomers was determined in 12 healthy subjects following oral administrati
Codeine (30 mg phosphate) was metabolized by eight human volunteers to the following six metabolites: codeine-6-glucuronide 81 .O+ 9.3 per cent, norcodeine 2.16? 1.44 per cent, morphine 0-562 0-39 per cent, morphine-3-glucuronide 2-10? 1-24 per cent, morphine-6-glucuronide 0-80k 0.63 per cent, and n