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Pharmacokinetics and efficacy of rectal versus oral sustained-release morphine in cancer patients

✍ Scribed by Timothy J. Wilkinson; Bridget A. Robinson; Evan J. Begg; Steven B. Duffull; Peter J. Ravenscroft; Jennifer J. Schnieder

Publisher
Springer
Year
1992
Tongue
English
Weight
444 KB
Volume
31
Category
Article
ISSN
0344-5704

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Immediate-release oral morphine, given every four hours in individually titrated doses, is effective in the control of severe cancer pain. To evaluate the analgesic efficacy of a controlled-release morphine sulfate preparation, MS Contin tablets (MSC, Purdue Frederick, Toronto, Ontario, Canada), aft