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Pharmacokinetics and efficacy of low-dose methotrexate in patients with rheumatoid arthritis

โœ Scribed by Yoshiko Hiraga; Yoshimitsu Yuhki; Katsumi Itoh; Kohji Tadano; Yasushi Takahashi; Masaya Mukai


Publisher
Springer
Year
2004
Tongue
English
Weight
347 KB
Volume
14
Category
Article
ISSN
1439-7595

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โœ Judith M. Dalrymple; Lisa K. Stamp; John L. O'Donnell; Peter T. Chapman; Mei Zha ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 282 KB ๐Ÿ‘ 2 views

## Abstract ## Objective There is evidence supporting a therapeutic range for methotrexate polyglutamate (MTXGlu) concentrations in the treatment of rheumatoid arthritis (RA). Knowledge of the pharmacokinetics of MTXGlu~1โ€“5~ is required for optimal timing of blood sampling. The aim of this study w