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Pharmacokinetics and clinical impact of all-trans retinoic acid in metastatic breast cancer: a phase II trial

✍ Scribed by Linda M. Sutton; Marc A. Warmuth; William P. Petros; Eric P. Winer

Publisher: Springer
Year: 1997
Tongue: English
Weight: 155 KB
Volume: 40
Category: Article
ISSN: 0344-5704
DOI: 10.1007/s002800050666

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## Background: Recent clinical trials with a combination of interferon (ifn alpha) and 13 cis-retinoic acid resulted in high response rates among women with locally advanced and metastatic carcinoma of the uterine cervix. the authors sought to amplify these observations by employing the isomer of 1