The pharmacokinetics of progesterone were characterized in ovariectomized female rats. Progesterone was administered intravenously at a dose of 500 pg kg-'. Serum progesterone concentrations were determined by radioimmunoassay. Serum concentrations of progesterone were best described by a two-compar
Pharmacokinetics after an intravenous single dose of the opioid ketobemidone in children
β Scribed by S. LUNDEBERG; N. STEPHANSON; P. LAFOLIE; G. L. OLSSON; C.-O. STILLER; S. EKSBORG
- Book ID
- 110909189
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 278 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0001-5172
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The pharmacokinetics of a new serotonin 5-HT 2 antagonist, deramciclane, was studied. Single oral doses of 1, 3, 6 and 10 mg kg -1 and intravenous doses of 1, 3 and 6 mg kg -1 were administered in beagle dogs. Moreover, the steady state pharmacokinetics of 1, 3 and 6 mg kg -1 doses were studied. Der