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Pharmacokinetic/pharmacodynamic modelling of cardiac toxicity in venlafaxine overdose

✍ Scribed by Bruno Mégarbane; Vanessa Bloch; Nicolas Deye; Frédéric J. Baud


Publisher
Springer
Year
2006
Tongue
English
Weight
91 KB
Volume
33
Category
Article
ISSN
1432-1238

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The prediction of chemotherapeutic efficacy is complicated by "protocol dependencies" in dose-effect and dose-toxicity relationships. It has been proposed that pharmacokinetic-pharmacodynamic mathematical models may allow characterization of chemotherapeutic protocol dependencies, and may facilitate