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Pharmacokinetic profile and adverse gastric effect of zinc-piroxicam in rats

✍ Scribed by Carlos A Tagliati; Elza Kimura; Michael S Nothenberg; Sı́lvia R.J.C Santos; Seizi Oga

Book ID
114234004
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
92 KB
Volume
33
Category
Article
ISSN
0306-3623

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✍ Lorin K. Roskos; F. Douglas Boudinot 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 514 KB

The effects of dose and sex on the pharmacokinetics of piroxicam were studied in the rat. Piroxicam was administered intravenously at doses of 050 and 5.0 mg kg-' to male and female rats. Plasma drug concentrations were determined by a highly sensitive highperformance liquid chromatographic techniqu