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Effect of Maytenus aquifolium extract on the pharmacokinetic and antiinflammatory effectiveness of Piroxicam in rats

✍ Scribed by E. Kimura; A.L.M. Albiero; R.K.N. Cuman; S.M. Caparroz-Assef; S. Oga; C.A. Bersani-Amado


Book ID
114306993
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
760 KB
Volume
7
Category
Article
ISSN
0944-7113

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The effects of dose and sex on the pharmacokinetics of piroxicam were studied in the rat. Piroxicam was administered intravenously at doses of 050 and 5.0 mg kg-' to male and female rats. Plasma drug concentrations were determined by a highly sensitive highperformance liquid chromatographic techniqu