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Pharmacokinetic Modulation of Plasma 5-Fluorouracil Concentrations to Potentiate the Antitumor Activity of Continuous Venous Infusion of 5-Fluorouracil

โœ Scribed by Fujii, Setsuro ;Fukushima, Masakazu ;Shimamoto, Yuji ;Shirasaka, Tetsuhiko


Book ID
108578814
Publisher
Wiley (Blackwell Publishing)
Year
1989
Tongue
English
Weight
239 KB
Volume
80
Category
Article
ISSN
0910-5050

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โœ Dr. Mukund S. Didolkar; Andre J. Jackson; David G. Covell; Alonzo P. Walker; Nat ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 565 KB

Continuous infusion chemotherapy via hepatic artery using newly available mechanical devices is frequently used to treat hepatic metastases to achieve a high concentration of 5-fluorouracil (5-FUra) in the hepatic circulation while minimizing systemic exposure. We compared four routes of intrahepati