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Effects of the Plasma Concentration of 5-Fluorouracil and the Duration of Continuous Venous Infusion of 5-Fluorouracil with an Inhibitor of 5-Fluorouracil Degradation on Yoshida Sarcomas in Rats

✍ Scribed by Fujii, Setsuro ;Shimamoto, Yuji ;Ohshimo, Hideyuki ;Imaoka, Takeshi ;Motoyama, Masaaki ;Fukushima, Masakazu ;Shirasaka, Tetsuhiko

Book ID
108578928
Publisher
Wiley (Blackwell Publishing)
Year
1989
Tongue
English
Weight
324 KB
Volume
80
Category
Article
ISSN
0910-5050

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## Abstract 5‐Fluorouracil was administered by continuous hepatic intra‐arterial infusion to eight patients with the diagnosis of cancer of the gastrointestinal tract and hepatic metastases. Its elimination characteristics were investigated to see if they correlated with therapeutic effect or reduc