The objective of this study was to examine the kinetics of the distribution of dehydroevodiamine (DHED) in the rat brain. After an intravenous infusion of 15 min (dose of 1-10 mg/kg), the temporal profiles of the plasma levels of DHED declined in a multiexponential manner. Moment analysis indicated
Pharmacokinetic Modeling of Non-Linear Brain Distribution of Fluvoxamine in the Rat
β Scribed by Marian Geldof; Jan Freijer; Ludy van Beijsterveldt; Meindert Danhof
- Publisher
- Springer US
- Year
- 2007
- Tongue
- English
- Weight
- 540 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0724-8741
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