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Pharmacokinetic Interaction between Neuroleptics and Tricyclic Antidepressants in the Rat

✍ Scribed by Gram, Lars F. ;Christiansen, Johannes ;Overø, Kerstin Fredricson

Book ID
114798990
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
464 KB
Volume
35
Category
Article
ISSN
0001-6683

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This study proposes a method capable of separating the pharmacodynamic from the pharmacokinetic component in the methamphetamine (MA) hyperactivity potentiation induced by antidepressants. Several antidepressants and neuroleptics, other centrally-acting drugs and the inhibitor of hepatic drug metabo