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Pharmacokinetic comparison of intravenous and intranasal administration of oxycodone

✍ Scribed by A. TAKALA; V. KAASALAINEN; T. SEPPÄLÄ; E. KALSO; K. T. OLKKOLA

Book ID
111754886
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
403 KB
Volume
41
Category
Article
ISSN
0001-5172

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Pharmacokinetics of midazolam in childre
Pharmacokinetics of midazolam in children: comparative study of intranasal and intravenous administration
✍ E. Rey; L. Delaunay; G. Pons; I. Murat; M. O. Richard; C. Saint-Maurice; G. Oliv 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 294 KB

Twelve children 1-5 y old were randomly assigned to receive midazolam 0.2 mg.kg-1 either by the intravenous (IV) or intranasal (IN) routes. After IN administration the rapid onset of absorption was observed (tmax 12 min). After both routes of administration the half-life was similar (2.2 h IN and 2.